Molecular Nomenclature quiz

Knowledge quiz
Questions 10
Criteria 60% to pass
Difficulty Hard
Play as logged
Get stats, badges and other cool features
(after login you will be redirected back to this page)

Play with friends competition
in real time
Online quiz competitions for the best score
Challenge your friends in real time
Create a competition of this quiz and see who of your friends gets the highest score. Share it, engage your friends and challenge them in real time to get the best score. Learn more about quiz competitions

Two variants were found in an exon of a gene by NGS: 79 G to T and 80 C to T; the gnomAD frequency at 79 is 0.49 and at 80 is 0.001. Which of the following is more correct?

What single letter is used to denote any substitution of a nucleotide at a particular position? Example: c.54G, substituted by A, T or C.

True or False? The 3’ rule for determining the position of a nucleotide variant in a sequence has no exceptions.

Beginning at the position shown in the picture, seven nucleotides were deleted and replaced by the following sequence: CGGGTGA. Which of the following is correct nomenclature for this change?

The following variants were detected in MSH2: c.1340_1341insGG and c.1168C>T, phase unknown. The correct DNA nomenclature for these variants is:

One carrier parent has a p.Phe447Leufs and the other carrier parent has a p.Leu390Phe. Protein nomenclature for a child who has inherited the first mutation but not the second should be described as:

A G to T substitution is detected at the position shown. What is the DNA and protein nomenclature?

For an X linked gene in a female, an SNV is correctly described as c.[76A>C];[76A=]. What is the correct way to describe the same change in a male?

A result is described as: c.2376[G>C];[=]. This indicates which of the following?

A G>A substitution at c.1096 is found to be homozygous by Sanger sequencing. What is the most correct way of describing this finding?

Results of quiz competition


SHARE with your friends

Enter your e-mail and get the opportunityto be notified of the competition results to your e-mail

Your result of the quiz

Your result of the survey


Quiz results

Survey results

Share with friends